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LRI Abstracts

 

Abstracts for Current Projects

Project abstracts are a primary source of information regarding the status and progress for LRI’s currently funded projects. These abstracts are provided each year by the principal investigators as a key part of their research agreement with LRI. Links to abstracts for each of these projects are located at the end of the project titles in the list below. Archives of final abstracts submitted for all completed projects can be found using the link located under the Search field to the right.

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Current LRI Research Project Portfolio: 19   

 

Project DescriptionPrincipal
Investigator
Research
Institution
Advancing Chemical Safety Assessment: Emerging Technologies and New Approaches
Human Phenomonitoring Pilot Project   (View) Wetmore, Barbara The Hamner Institutes for Health Sciences
Reverse Causality of Polybrominated Diphenyl Ethers and Polychlorinated Biphenyls   (View) Clewell, Harvey J. III The Hamner Institutes for Health Sciences
Application of Genomics in Chemical Risk Assessment—An NCEA-Hamner Collaboration   (View) Thomas, Russell The Hamner Institutes for Health Sciences
Development and Validation of Organotypic In Vitro Models of the Liver for Toxicity Testing   (View) LeCluyse, Edward The Hamner Institutes for Health Sciences
Assessing the Exposure-Dose-Toxicity Relationship Within the EPA’s ToxCast™ Program – Project Extension   (View) Wetmore, Barbara The Hamner Institutes for Health Sciences
Development of In Vitro-To-In Vivo (IVIVE) Extrapolation Methods for Chemical Disposition   (View) Clewell, Harvey J. III The Hamner Institutes for Health Sciences
Incorporating Dosimetry and Exposure Considerations in Interpretation of ToxCast™ Data: Initial Approaches   (View) Hays, Sean Summit Toxicology
Characterizing Risks of Chemicals Exhibiting Extensive Low Dose Clearance in the Gut, Liver, and Blood: Dietary Chlorpyrifos as a Case Example   (View) Price, Paul S. Dow Chemical Co.
Investigation of the Application of Innovative Risk Assessment Approaches for Receptor-Mediated Endpoints: A Case Study with DEHP (Di(2-ethylhexyl) phthalate)   (View) Shipp, Annette M. ENVIRON International
Validation Studies of the Intact Adult Rat Male Screening Assay (IAMRSA)   (View) Borghoff, Susan Integrated Laboratory Systems, INC.
Further Validation Studies of the Intact Adult Male Rat Screening Assay (IAMRSA) for Two Chemicals   (View) Tyl, Rochelle W. RTI International
Innovations in Exposure Science: Improving Our Understanding of Health Impacts of Chemicals
USEtox Prioritization Indices for Chemical Exposure from Consumer Products (USEtoxPI)   (View) Jolliet, Olivier University of Michigan
Advancing Exposure Models to Capture a Broad Continuum of Exposure Scenarios   (View) Bennett, Deborah University of California, Davis
Facilitating the Centralization and Integration of Exposure Data through Exposure Ontology Development and Expanded Accessibility to Exposure Studies   (View) Mattingly, Carolyn Mount Desert Island Biological Laboratory
Biomarkers of Cumulative Exposure   (View) Rappaport, Stephen M. University of California, Berkeley
An Exposure Ontology Curation Structured on the Exposome Concept   (View) McKone, Thomas E. University of California, Berkeley
Intra-Individual Variability in Biomarker Concentrations: Phase 1 - Literature Review and Manuscript   (View) Hays, Sean Summit Toxicology
New Study Designs for Interpretation of Chemical Exposure Data   (View) Schisterman, Enrique F. National Institute of Child Health and Human Development
New Study Designs and Methods to Evaluate Gene and Environmental Chemical Interaction Data   (View) Schisterman, Enrique F. National Institute of Child Health and Human Development